Logo: REBLOZYL® (luspatercept-aamt)

Ready for your
REBLOZYL journey?

Ask your doctor what's next for your MDS-related anemia so you get the right medicine for you at the right time.

Treatment for MDS-related anemia doesn’t have to be a weekly routine—and with REBLOZYL, it isn’t

If you’ve been prescribed REBLOZYL, you might want to understand what starting treatment may be like.

How will I receive REBLOZYL?

You will receive a REBLOZYL injection once every 3 weeks by your healthcare team at their office


  • REBLOZYL is an injection given under your skin, in your upper arm, thigh, or stomach
  • Needles used for injections that go under your skin are smaller than those used for injections that go into your muscle, such as those used for most vaccines
  • Note: Your doctor may adjust dosing during visits to ensure your treatment is tailored to you
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Before each REBLOZYL injection, your healthcare team will:

Do a blood test to check your hemoglobin (Hgb) levels

Hgb levels can be connected to your anemia symptoms. Testing Hgb levels can help your healthcare team understand the severity of your anemia and whether your current REBLOZYL dose is working or if an adjustment is needed. If your Hgb level jumps too high, your dose may be paused for a period of time.

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Ask if you have had any red blood cell (RBC) transfusions since your last REBLOZYL injection

How often you need RBC transfusions and any changes in their frequency is important to share with your healthcare team. This will help them understand how well your current REBLOZYL dose is working or if you might need an adjustment.

Icon: IV for blood transfusion

Knowing about your Hgb levels and RBC transfusions helps your healthcare team see the full picture and understand how you are responding to REBLOZYL and how your dose may be adjusted.

How can I get the most out of REBLOZYL?

Working closely with your healthcare team by tracking and sharing important information will help you get the most out of treatment with REBLOZYL. It will also help your team better understand how your REBLOZYL dose is working for you.

Start tracking the following to discuss at your appointments:

  • The severity of your symptoms and any side effects affecting your day-to-day life
  • Blood test results, including Hgb levels
    • Remember: Levels will be tested every appointment to see how you're tracking toward the Hgb goals your healthcare team
      sets for you
  • Any RBC transfusion(s) received, including the number of RBC units in each transfusion
  • Your REBLOZYL dose and any changes to it over time
    • Remember: Dose adjustments are a normal and expected part of treatment, especially during your first few visits
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How can I prepare for my appointments?

Your appointments are your time. Make sure you take the time to talk with your healthcare team about how you're feeling. It can be hard to remember any new or changing symptoms since your last visit. Don't be shy about asking a loved one to help you prepare information for your upcoming discussions with your healthcare team.

Doctor Discussion Guide

Stronger conversations can lead to better treatment outcomes, and we want to set you up to have the best conversations with your healthcare team.

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Treatment Tracker

Keeping track of your symptoms and hemoglobin levels in one place can help your healthcare team stay informed and help you see how you are advancing toward your goals.

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Badge: First line Treatment REBLOZYL® (luspatercept-aamt)

I'm thinking about REBLOZYL as my FIRST-LINE treatment

In a clinical study that compared REBLOZYL and epoetin alfa, an erythropoiesis-stimulating agent (ESA), the main goal was to:

  • Raise Hgb levels by more than 1.5 g/dL
  • Stop the need for RBC transfusions for at least 12 weeks

REBLOZYL worked better and longer for more people than epoetin alfa did. You and your healthcare team may be able to get improved results by starting your treatment journey with REBLOZYL. Ask your healthcare team if REBLOZYL is the right FIRST step.

SEE THE RESULTS

Badge: Second line Treatment REBLOZYL® (luspatercept-aamt)

I’m thinking about REBLOZYL as my SECOND-LINE treatment

REBLOZYL can help treat anemia in people who’ve tried ESAs without success. REBLOZYL may help reduce the number of RBC transfusions you may need over time. Ask your healthcare team if a switch to REBLOZYL would help.

SEE THE RESULTS
Banner: Your REBLOZYL® (luspatercept-aamt) Connection™

We have resources for you along every step of your treatment journey

If you're ready to ask about REBLOZYL, we're ready to help you feel confident. Your REBLOZYL Connection is an educational program designed to help you understand treatment with REBLOZYL and provide resources so you can take a more active role with your care.